Prof Minja Gerber is an NRF-rated (C2 since 2019) Research Professor at Pharmacen™, North-West University (NWU), and a specialist in transdermal, dermal and topical drug delivery, skin diffusion and nano-drug delivery systems. Her expertise lies in understanding and engineering how active pharmaceutical and cosmeceutical ingredients interact with, penetrate and move through the skin. Her research integrates nano-carriers, including nano-emulsions, nanoparticles, nano-emulgels and vesicular systems, with dermal cytotoxicity and wound-healing research to develop safer, more effective skin delivery technologies.
Prof Gerber leads the Drug Delivery subprogramme and serves as Head of Cutaneous Drug Delivery and Cosmeceutical Research (CDDCR), Head of Pharmacen™ Skin Studies Services, and Chairperson of the Scientific Committee: Drug Delivery. She is also the internal facilitator of the Postgraduate diploma (PG Dip) in Cosmetic Product Formulation.
A defining feature of her work is the translation of advanced skin-delivery science into research, innovation and real-world applications. Through Pharmacen™ Skin Studies Services, Prof Gerber leads collaborative and contract research projects for higher education institutions, pharmaceutical and cosmetic industries, and government. These projects encompass formulation development, skin diffusion and permeation studies, dermal delivery assessment, safety evaluation and product performance testing; creating a platform for strategic collaboration, technology translation and third-stream income generation for NWU.
Since 2006, Prof Gerber has mentored the next generation of researchers, supervising MSc and PhD students and postdoctoral fellows, while contributing to numerous international scientific publications. She is an active reviewer for international journals and funding agencies and has presented her research nationally and internationally. In 2012, she completed a research sabbatical at Leiden University under the guidance of Prof Joke Bouwstra, internationally recognised for her work in skin drug delivery.
Prof Gerber serves on the EXCO of the South African Chapter of the Controlled Release Society, representing Transdermal and Topical Drug Delivery in South Africa and at NWU.
Potchefstroom campus, Building G2, Ground floor, Office G11
1 Gerber, M., Breytenbach, J.C., Hadgraft, J. and Du Plessis, J. 2006. Synthesis and transdermal properties of acetylsalicylic acid and selected esters. International Journal of Pharmaceutics, 310(1-2):31-36.
Boloka: http://hdl.handle.net/10394/14748
ORCiD: https://doi.org/10.1016/j.ijpharm.2005.11.018
Research Gate: https://www.researchgate.net/publication/7330490_Synthesis_and_transder…
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2 Gerber, M., Breytenbach, J.C. and Du Plessis, J. 2008. Transdermal penetration of zalcitabine, lamivudine and synthesised N-acyl lamivudine esters. International Journal of Pharmaceutics, 351(1-2):186-193.
Boloka: http://hdl.handle.net/10394/2784
ORCiD: https://doi.org/10.1016/j.ijpharm.2007.09.040
Research Gate: https://www.researchgate.net/publication/5841282_Transdermal_penetratio…
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3 Holmes, E-M., Breytenbach, J.C., Gerber, M. and Du Plessis, J. 2010. Synthesis and transdermal penetration of stavudine-5'-esters. Medicinal Chemistry, 6(5):271-276.
Boloka: http://hdl.handle.net/10394/14814
ORCiD: https://doi.org/10.2174/157340610793358873
Research Gate: https://www.researchgate.net/publication/233645086_Synthesis_and_Transd…
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4 Fox, L.T., Gerber, M., Du Preez, J.L., Grobler, A. and Du Plessis, J. 2011. Topical and transdermal delivery of L-carnitine. Skin Pharmacology and Physiology, 24(6):330-336.
Boloka: http://hdl.handle.net/10394/7869
ORCiD: https://doi.org/10.1159/000330385
Research Gate: https://www.researchgate.net/publication/51563072_Topical_and_Transderm…
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5 Fox, L.T., Gerber, M., Du Plessis, J. and Hamman, J.H. 2011. Transdermal drug delivery enhancement by compounds of natural origin. Molecules, 16(12):10507-10540.
Boloka: http://hdl.handle.net/10394/14753
ORCiD: https://doi.org/10.3390/molecules161210507
Research Gate: https://www.researchgate.net/publication/253342367_Transdermal_Drug_Del…
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6 Fox, L.T., Du Plessis, J., Gerber, M., Van Zyl, S., Boneschans, B. and Hamman, J.H. 2014. In vivo skin hydration and anti-erythema effects of Aloe vera, Aloe ferox and Aloe marlothii gel materials after single and multiple application. Pharmacognosy Magazine, 10(38):S392-S403.
Boloka: http://hdl.handle.net/10394/16393
ORCiD: https://doi.org/10.4103/0973-1296.133291
Research Gate: https://www.researchgate.net/publication/263745441_In_Vivo_skin_hydrati…
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7 Fox, L.T., Gerber, M., Du Preez, J.L., Du Plessis, J. and Hamman, J.H. 2015. Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox. Journal of Pharmacy and Pharmacology, 67(1):96-106.
Boloka: http://hdl.handle.net/10394/14751
ORCiD: https://doi.org/10.1111/jphp.12311
Research Gate: https://www.researchgate.net/publication/265388950_Skin_permeation_enha…
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8 Jacobs, G.A., Gerber, M., Malan, M.M., Du Preez, J.L., Fox, L.T. and Du Plessis, J. 2016. Topical delivery of acyclovir and ketoconazole. Drug Delivery, 23(2):631-641.
Boloka: http://hdl.handle.net/10394/14756
ORCiD: https://doi.org/10.3109/10717544.2014.933283
Research Gate: https://www.researchgate.net/publication/263777202_Topical_delivery_of_…
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9 Chinembiri, T.N., Du Plessis, L.H., Gerber, M., Hamman, J.H. and Du Plessis, J. 2014. Review of natural compounds for potential skin cancer treatment. Molecules, 19(8):11679-11721.
Boloka: http://hdl.handle.net/10394/16337
ORCiD: https://doi.org/10.3390/molecules190811679
Research Gate: https://www.researchgate.net/publication/264636991_Review_of_Natural_Co…
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10 Shahzad, Y., Khan, I.U., Hussain, T., Alamgeer, Serra, C.A., Rizvi, S.A.A., Gerber, M. and Du Plessis, J. 2014. Bioactive albumin-based carriers for tumour chemotherapy. Current Cancer Drug Targets, 14(8):752-763.
Boloka: http://hdl.handle.net/10394/15931
ORCiD: http://dx.doi.org/10.2174/1568009614666141028100640
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11 Shahzad, Y., Louw, R., Gerber, M. and Du Plessis, J. 2015. Breaching the skin barrier through temperature modulations. Journal of Controlled Release, 202:1-13.
Boloka: http://hdl.handle.net/10394/14758
ORCiD: https://doi.org/10.1016/j.jconrel.2015.01.019
Research Gate: https://www.researchgate.net/publication/271196592_Breaching_the_Skin_B…
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12 Chinembiri, T.N., Gerber, M., Du Plessis, L.H., Du Preez, J.L. and Du Plessis, J. 2015. Topical delivery of 5-fluorouracil from Pheroid™ formulations and the in vitro efficacy against human melanoma. AAPS PharmSciTech, 16(6):1390-1399.
Boloka: http://hdl.handle.net/10394/14760
ORCiD: https://doi.org/10.1208/s12249-015-0328-7
Research Gate: https://www.researchgate.net/publication/276066356_Topical_Delivery_of_…
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13 Viljoen, J.M., Cowley, A., Du Preez, J.L., Gerber, M. and Du Plessis, J. 2015. Penetration enhancing effects of selected natural oils utilized in topical dosage forms. Drug Development and Industrial Pharmacy, 41(12):2045-2054.
Boloka: http://hdl.handle.net/10394/14757
ORCiD: https://doi.org/10.3109/03639045.2015.1047847
Research Gate: https://www.researchgate.net/publication/277522269_Penetration_enhancin…
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14 Kilian, D., Shahzad, Y., Fox, L., Gerber, M. and Du Plessis, J. 2015. Vesicular carriers for skin drug delivery: The Pheroid™ technology. Current Pharmaceutical Design, 21(20):2758-2770.
Boloka: http://hdl.handle.net/10394/14762
ORCiD: https://doi.org/10.2174/1381612821666150428125812
Research Gate: https://www.researchgate.net/publication/275545984_Vesicular_Carriers_f…
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15 Gerber, G.S.F.W., Fox, L.T., Gerber, M., Du Preez, J.L., Van Zyl, S., Boneschans, B. and Du Plessis, J. 2015. Stability, clinical efficacy and antioxidant properties of Honeybush extracts in semi-solid formulations. Pharmacognosy Magazine, 11(44):S337-S351.
Boloka: http://hdl.handle.net/10394/14763
ORCiD: http://dx.doi.org/10.4103/0973-1296.166063
Research Gate: https://www.researchgate.net/publication/277528283_Stability_clinical_e…
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16 Burger, C., Gerber, M., Du Preez, J.L. and Du Plessis, J. 2015. Optimised transdermal delivery of pravastatin. International Journal of Pharmaceutics, 496(2):518-525.
Boloka: http://hdl.handle.net/10394/16001
ORCiD: https://doi.org/10.1016/j.ijpharm.2015.10.034
Research Gate: https://www.researchgate.net/publication/283293144_Optimised_transderma…
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17 Aucamp, M.E., Csongradi, C., Gerber, M. and Du Plessis, J. 2016. A novel RP-HPLC method for the detection and quantification of roxithromycin in topical delivery studies. Die Pharmazie, 71(4):175-176.
Boloka: http://hdl.handle.net/10394/16003
ORCiD: https://doi.org/10.1691/ph.2016.5165
Research Gate: https://www.researchgate.net/publication/302886710_A_novel_RP-HPLC_meth…
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18 Van Zyl, L., Du Preez, J., Gerber, M., Du Plessis, J. and Viljoen, J. 2016. Essential fatty acids as transdermal penetration enhancers. Journal of Pharmaceutical Sciences, 105(1):188-193.
Boloka: http://hdl.handle.net/10394/15979
ORCiD: https://doi.org/10.1016/j.xphs.2015.11.032
Research Gate: https://www.researchgate.net/publication/290480850_Essential_Fatty_Acid…
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19 Kilian, D., Lemmer, H.J.R., Gerber, M., Du Preez, J.L. and Du Plessis, J. 2016. Exploratory data analysis of the dependencies between skin permeability, molecular weight and log P. Die Pharmazie, 71(6):311-319.
Boloka: http://hdl.handle.net/10394/16742
ORCiD: https://doi.org/10.1691/ph.2015.5170
Research Gate: https://www.researchgate.net/publication/305004985_Exploratory_data_ana…
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20 Dwivedi, A., Mazumder, A., Fox, L.T., Brümmer, A., Gerber, M., Du Preez, J.L., Haynes, R.K. and Du Plessis, J. 2016. In vitro skin permeation of artemisone and its nano-vesicular formulations. International Journal of Pharmaceutics, 503(1-2):1-7.
Boloka: http://hdl.handle.net/10394/16743
ORCiD: https://doi.org/10.1016/j.ijpharm.2016.02.041
Research Gate: https://www.researchgate.net/publication/296634097_In_vitro_skin_permea…
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21 Venter, T., Fox, L.T., Gerber, M., Du Preez, J.L., Van Zyl, S., Boneschans, B. and Du Plessis, J. 2016. Physical stability and clinical efficacy of Crocodylus niloticus oil lotion. Revista Brasileira de Farmacognosia/Brazilian Journal of Pharmacognosy, 26(4):521-529.
Boloka: http://hdl.handle.net/10394/16741
ORCiD: https://doi.org/10.1016/j.bjp.2016.03.011
Research Gate: https://www.researchgate.net/publication/303501238_Physical_stability_a…
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22 Mazumder, A., Dwivedi, A., Fox, L.T., Brümmer, A., Du Preez, J.L., Gerber, M. and Du Plessis, J. 2016. In vitro skin permeation of sinigrin from its phytosome complex. Journal of Pharmacy and Pharmacology, 68(12):1577-1583.
Boloka: http://hdl.handle.net/10394/17629
ORCiD: https://doi.org/10.1111/jphp.12594
Research Gate: https://www.researchgate.net/publication/308941588_In_vitro_skin_permea…
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23 Fox, L., Csongradi, C., Aucamp, M., Du Plessis, J. and Gerber, M. 2016. Treatment modalities for acne. Molecules, 21(8):1063.
Boloka: http://hdl.handle.net/10394/18747
ORCiD: https://doi.org/10.3390/molecules21081063
Research Gate: https://www.researchgate.net/publication/306132621_Treatment_Modalities…
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24 Burger C, Shahzad Y, Brümmer A, Du Plessis J, Gerber M. 2017. Traversing the skin barrier through nano-emulsions. Current Drug Delivery, 14(4):458-472.
Boloka: http://hdl.handle.net/10394/18748
ORCiD: http://dx.doi.org/10.2174/1567201813666160824125444
Research Gate: https://www.researchgate.net/publication/306946199_Traversing_the_skin_…
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25 Csongradi, C., Du Plessis, J., Aucamp, M.E. and Gerber, M. 2017. Topical delivery of roxithromycin solid-state forms entrapped in vesicles. European Journal of Pharmaceutics and Biopharmaceutics, 114:96-107.
Boloka: http://hdl.handle.net/10394/20668
ORCiD: https://doi.org/10.1016/j.ejpb.2017.01.006
Research Gate: https://www.researchgate.net/publication/312598304_Topical_delivery_of_…
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26 Fox, L.T., Mazumder, A., Dwivedi, A., Gerber, M., Du Plessis, J. and Hamman, J.H. 2017. In vitro wound healing and cytotoxic activity of the gel and whole-leaf materials from selected aloe species. Journal of Ethnopharmacology, 200:1-7.
Boloka: http://hdl.handle.net/10394/20712
ORCiD: https://doi.org/10.1016/j.jep.2017.02.017
Research Gate: https://www.researchgate.net/publication/313733289_In_vitro_wound_heali…
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27 Chinembiri, T.N., Gerber, M., Du Plessis, L.H., Du Preez, J.L., Hamman, J.H. and Du Plessis, J. 2017. Topical delivery of Withania somnifera crude extracts in niosomes and solid lipid nanoparticles. Pharmacognosy Magazine, 13(51):S663-S671.
Boloka: http://hdl.handle.net/10394/25904
ORCiD: https://doi.org/10.4103/pm.pm_489_16
Research Gate: https://www.researchgate.net/publication/320352242_Topical_Delivery_of_…
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28 Du Preez, J.L., Aucamp, M.E., Burger, C., Gerber, M., Viljoen, J.M., Van Zyl, L. and Du Plessis, J. 2018. Development and validation of the simultaneous determination of artemisone, clofazimine and decoquinate with HPLC. Die Pharmazie, 73(3):139-142.
Boloka: http://hdl.handle.net/10394/26679
ORCiD: https://doi.org/10.1691/ph.2018.7127
Research Gate: https://www.researchgate.net/publication/323830632_Development_and_vali…
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29 Burger, C., Aucamp, M., Du Preez, J., Haynes, R.K., Ngwane, A., Du Plessis, J. and Gerber M. 2018. Formulation of natural oil nano-emulsions for the topical delivery of clofazimine, artemisone and decoquinate. Pharmaceutical Research, 35(10):186.
Boloka: http://hdl.handle.net/10394/30744
ORCiD: https://doi.org/10.1007/s11095-018-2471-9
Research Gate: https://www.researchgate.net/publication/326884088_Formulation_of_Natur…
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30 Marais, S., Du Preez, J.L., Du Plessis, L.H., Du Plessis, J. and Gerber, M. 2019. Determination of lovastatin, mevastatin, rosuvastatin and simvastatin with HPLC by means of gradient elution. Die Pharmazie, 74(11):658-660.
Boloka: http://hdl.handle.net/10394/33691
ORCiD: https://doi.org/10.1691/ph.2019.8192
Research Gate: https://www.researchgate.net/publication/337399487_Determination_of_lov…
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31 Maree S, Du Preez JL, Du Plessis LH, Du Plessis J, Gerber M. 2020. A novel HPLC method developed and validated for the detection and quantification of atorvastatin, fluvastatin, pitavastatin and pravastatin during transdermal delivery studies. Die Pharmazie, 75(5):164-166.
Boloka: http://hdl.handle.net/10394/34597
ORCiD: DOI: 10.1691/ph.2020.0007
Research Gate: https://www.researchgate.net/publication/341355349_A_novel_HPLC_method_…
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Sithole MN, Marais S, Maree SM, Du Plessis LH, Du Plessis J, Gerber M. 2021. Development and characterization of nanoemulsions and nano-emulgels for transdermal delivery of statins. Expert Opinion on Drug Delivery, 18(6):789-801.
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ORCiD: https://doi.org/10.1080/17425247.2021.1867533
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Sithole MN, Oosthuysen E, Van Jaarsveld J, Du Preez JL, Du Plessis J, Gerber M. 2021. Development and validation of an HPLC method to be used for simultaneous detection and quantification of different statins after ex vivo skin diffusion studies. Die Pharmazie, 76(12):583-587.
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ORCiD: DOI: 10.1691/ph.2021.1164
Research Gate: https://www.researchgate.net/publication/357658197_Development_and_vali…
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Chinembiri TN, Du Plessis LH, Willers C, Davids LM, Gerber M, Du Plessis J. 2022. In vitro anti-melanoma efficacy and selectivity of Withania somnifera. Revista Brasileira de Farmacognosia/Brazilian Journal of Pharmacognosy, 32(3):421-432.
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ORCiD: https://doi.org/10.1007/s43450-022-00259-5
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https://www.researchgate.net/publication/360578909_In_Vitro_Anti-melano…
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Van Jaarsveld E, Du Plessis J, Du Preez JL, Shahzad Y, Gerber M. 2022. Formulation and characterisation of artemether-loaded nano-emulsion for topical applications. Journal of Drug Delivery Science and Technology, 73:103449.
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ORCiD: https://doi.org/10.1016/j.jddst.2022.103449
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Olivier, D., Van der Kooy, F. and Gerber, M. 2023. Geographical and seasonal phytochemical variation of Artemisia afra Jacq. ex Willd. Phytochemical Analysis, 34(2):175-185.
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ORCiD: https://doi.org/10.1002/pca.3191
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Louw, E.-V., Liebenberg, W., Willers, C., Dube, A., Aucamp, M.E. and Gerber, M. 2023. Comparative study on the topical and transdermal delivery of diclofenac incorporated in nano-emulsions, nano-emulgels and a colloidal suspension. Drug Delivery and Translational Research, 13(5):1372-1389.
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ORCiD: https://doi.org/10.1007/s13346-022-01267-7
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Ponte, M., Liebenberg, W. and Gerber, M. 2023. Formulation and in vitro skin diffusion of colchicine using different drug delivery vehicles. Journal of Drug Delivery Science and Technology, 88:104898.
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ORCiD: https://doi.org/10.1016/j.jddst.2023.104898
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Gerber, M., Oosthuysen, E., Van Jaarsveld, J.R., Shahzad, Y. and Du Plessis, J. 2023. Grapeseed oil nanoemulsions and nanoemulgels for transdermal delivery of a series of statins. Journal of Drug Delivery Science and Technology, 88:104900.
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ORCiD: https://doi.org/10.1016/j.jddst.2023.104900
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Mouton, M., Gerber, M. and Van der Kooy, F. 2024. Validation of a fast LC-PDA method for the quantification of cannabinoids in commercial tea samples. Revista Brasileira de Farmacognosia/Brazilian Journal of Pharmacognosy, 34:197-201.
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ORCiD: https://doi.org/10.1007/s43450-023-00461-z
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Myburgh, J., Liebenberg, W., Willers, C., Dube, A. and Gerber, M. 2023. Investigation and evaluation of the transdermal delivery of ibuprofen in various characterized nano-drug delivery systems. Pharmaceutics, 15(10):2413.
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ORCiD: https://doi.org/10.3390/pharmaceutics15102413
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Mouton, M., Gerber, M. and Van der Kooy, F. 2024. Cure-all cannabidiol? The cannabidiol content of commercial products. Phytomedicine Plus, 4(1):100520.
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ORCiD: https://doi.org/10.1016/j.phyplu.2023.100520
Research Gate:
https://www.researchgate.net/publication/376135075_Cure-all_Cannabidiol…
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De Vos, L., Gerber, M., Liebenberg, W., Wessels, J.C. and Lemmer, H.J.R. 2024. Co-processed crystalline solids of ivermectin with Span® 60 as solubility enhancers of ivermectin in natural oils. AAPS PharmSciTech, 25(4):67.
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ORCiD: https://doi.org/10.1208/s12249-024-02783-0
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