Medical scientist Puseletso Manyaka-Lesofe recently stepped up to change the narrative regarding the representation of females in science. Puseletso joined as a panellist at the launch of the groundbreaking InnovateHER project, which was hosted at the University of Johannesburg on Saturday, 10 May, reaffirming her commitment to empowering young women.

The event brought together Grade 12 learners from across Gauteng alongside passionate professionals and guest speakers to encourage young women to step into the science, technology, engineering and mathematics (STEM) fields – spaces where women are vastly underrepresented. Not only does this underrepresentation limit women’s contributions to vital sectors, but it hinders diversity and innovation within the workforce.

Reflecting on her role as a panellist, Puseletso stated: “I was privileged to share my journey in STEM with the learners. The questions posed to us were deeply reflective, and they reignited in me the very passion that brought me into this field. It was powerful to see the young women listening, asking questions and envisioning their own paths in science, technology and innovation.”

Among the keynote speakers were Dr Judy Dlamini, chancellor of the University of the Witwatersrand (WITS) and Dr Mamoeletsi Mosia, managing director of the South African Agency for Science and Technology Advancement (NRF-SAASTA). Prof Tebogo Mashifana, advisory board member of Koako Green Energy Solutions, Gugulethu Zwane, Boitumelo Lekhoe, Khanyisile Masemola, Pabalelo Banks and Dr Moleboheng Mokhele-Ramulumo were the other expert panellists.

For Puseletso, her experience among fellow trailblazers carries profound significance. “These remarkable leaders reminded us that representation matters,” she reflected. “Young women deserve to see reflections of themselves in the highest levels of academia, business and innovation.”

In addition to her advocacy on the stage, Puseletso also contributed to the InnovateHER guide, a booklet developed specifically for female Grade 12 learners. This guide is packed with practical tools for exam preparation, university readiness and career development – serving as a confidence booster for young women looking to break into a male-dominated environment. It is a document that provides young women who may not yet envision themselves in lab coats or leading technology businesses with a clearer path to their ambitions.

For Puseletso, it is important to have resources specifically tailored for young women to pursue STEM fields.

“Tailored materials foster a sense of belonging and show young women that their voices, perspectives and talents are not only welcome but essential in science, technology, engineering and mathematics,” she said.

She elaborated: “Young women often face unique social, cultural and systemic barriers in accessing and thriving in STEM fields. These resources do not just provide information – they offer representation, mentorship and affirmation. They speak directly to the lived experiences of young women, building confidence and dismantling the myth that STEM is only for men.”

According to Puseletso, the guide is meant to empower and encourage young women to navigate their paths. “I hope the InnovateHER guide becomes a beacon of hope and clarity for young women who are uncertain about their place in STEM, and my dream is that it reaches townships and rural areas where they need it the most. I wish for every girl who reads it to feel seen, equipped and inspired to pursue a future in STEM with confidence,” she stated.

The opportunity to use her own experience to encourage and uplift young women was one of the most rewarding parts of contributing to the study guide.

“Knowing that my story, once filled with questions, setbacks and hard-won triumphs, could now serve as a guidepost for someone else was extremely satisfying. Contributing to the guide allowed me to give back in a practical, long-term way, helping to unlock the potential of the next generation,” Puseletso concluded.

Puseletso Manyaka-Lesofe is a mentor to the next generation. She is passionate about guiding aspiring medical scientists towards research, career growth and leadership opportunities.

The InnovateHER guide features comprehensive resources, from academic achievement to career planning strategies, specifically tailored for female STEM students.