My interests are in behavioural neuroscience and neuro- and psychopharmacology, with a special interest in anxiety and stress related disorders, including depression, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD) and schizophrenia. My research focuses on mechanisms of synaptic and cellular signalling, and especially their relevance in the pathology and pharmacology of stress-related disorders. I have successfully developed a number of in vivo animal models of human psychiatric disorders, specifically major depression, schizophrenia, PTSD, OCD and tardive dyskinesia (TD). The aim of my work is to develop and validate new and existing animal models of anxiety and stress-related disorders and to apply these models to learning more of the neurobiology and drug treatment response in human psychiatric disorders.