School of Pharmacy

Minja Gerber

BELINDA BANTHAM — Thu, 23 May 2024 06:41:34 +0000

Minja Gerber BELINDA BANTHAM Thu, 05/23/2024 - 08:41

Cosmeceuticals

Drug delivery

Pharmaceutics

Research Professor

Topical drug delivery

Transdermal drug delivery

Prof

Research Professor

Minja

Gerber

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School of Pharmacy

Prof Minja Gerber is a full-time, NRF-rated (C2 - since 2019) researcher at Pharmacen™, NWU. She acts as Subprogramme leader: Drug Delivery; Chairperson of the Scientific Committee: Drug Delivery; Head: Cosmeceutical Research; Manager: Transdermal and Topical Drug Delivery Laboratories; Head: Pharmacen™ Skin Studies Services, and Internal facilitator: PG Dip (Cosmetic Product Formulation).

Prof Gerber is registered at the South African Pharmacy Council (SAPC), she is an EXCO member of The South African Chapter of the Controlled Release Society (CRS) – representing Transdermal and Topical Drug Delivery in South Africa and the North-West University and a member of The Pharmaceutical Society of South Africa (PSSA); Society of Cosmetic Chemists South Africa (Coschem), Cosmetic, Toiletry & Fragrance Association of South Africa (CTFA) and The Society for Advanced Cell Culture Modelling for Africa (SACCMA). She also serves on the Faculty Board and the Research and Innovation Committee of Health Sciences, NWU.

Since 2006, she has mentored various postdoctoral fellows and postgraduate students (MSc and PhD). She is the author/co-author of numerous international publications and has presented her research at different scientific conferences, nationally and internationally. Prof Gerber regularly acts as reviewer for numerous internationally accredited journals and as external reviewer for grant proposals, nationally and internationally (i.e., Chile and France). She has received several research grants of which she was the principal investigator and completed a Sabbatical at the Division of Drug Delivery Technology, LACDR (Leiden Academic Centre for Drug Research), Leiden University, The Netherlands under the guidance of Prof Joke Bouwstra in 2012.

Prof Gerber focusses on the development of novel research technologies in transdermal and topical drug delivery coupled with dermal toxicity, wound healing, and nano-drug delivery vehicles (i.e., nano-emulsions, nanoparticles, nano-emulgels, vesicles, etc.) for the topical application of different actives (pharmaceutical or cosmeceutical) to enhance percutaneous absorption and to assess delivery into and through the skin. She also investigates the release and delivery of actives with regards to the skin for the industry (pharmaceutical and cosmeceutical).

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https://health-sciences.nwu.ac.za/pharmacen/prof-minja-gerber

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Pharmaceutics

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1 Gerber, M., Breytenbach, J.C., Hadgraft, J. and Du Plessis, J. 2006. Synthesis and transdermal properties of acetylsalicylic acid and selected esters. International Journal of Pharmaceutics, 310(1-2):31-36.

Boloka: http://hdl.handle.net/10394/14748

ORCiD: https://doi.org/10.1016/j.ijpharm.2005.11.018

Research Gate: https://www.researchgate.net/publication/7330490_Synthesis_and_transder…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

2 Gerber, M., Breytenbach, J.C. and Du Plessis, J. 2008. Transdermal penetration of zalcitabine, lamivudine and synthesised N-acyl lamivudine esters. International Journal of Pharmaceutics, 351(1-2):186-193.

Boloka: http://hdl.handle.net/10394/2784

ORCiD: https://doi.org/10.1016/j.ijpharm.2007.09.040

Research Gate: https://www.researchgate.net/publication/5841282_Transdermal_penetratio…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

3 Holmes, E-M., Breytenbach, J.C., Gerber, M. and Du Plessis, J. 2010. Synthesis and transdermal penetration of stavudine-5'-esters. Medicinal Chemistry, 6(5):271-276.

Boloka: http://hdl.handle.net/10394/14814

ORCiD: https://doi.org/10.2174/157340610793358873

Research Gate: https://www.researchgate.net/publication/233645086_Synthesis_and_Transd…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

4 Fox, L.T., Gerber, M., Du Preez, J.L., Grobler, A. and Du Plessis, J. 2011. Topical and transdermal delivery of L-carnitine. Skin Pharmacology and Physiology, 24(6):330-336.

Boloka: http://hdl.handle.net/10394/7869

ORCiD: https://doi.org/10.1159/000330385

Research Gate: https://www.researchgate.net/publication/51563072_Topical_and_Transderm…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

5 Fox, L.T., Gerber, M., Du Plessis, J. and Hamman, J.H. 2011. Transdermal drug delivery enhancement by compounds of natural origin. Molecules, 16(12):10507-10540.

Boloka: http://hdl.handle.net/10394/14753

ORCiD: https://doi.org/10.3390/molecules161210507

Research Gate: https://www.researchgate.net/publication/253342367_Transdermal_Drug_Del…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

6 Fox, L.T., Du Plessis, J., Gerber, M., Van Zyl, S., Boneschans, B. and Hamman, J.H. 2014. In vivo skin hydration and anti-erythema effects of Aloe vera, Aloe ferox and Aloe marlothii gel materials after single and multiple application. Pharmacognosy Magazine, 10(38):S392-S403.

Boloka: http://hdl.handle.net/10394/16393

ORCiD: https://doi.org/10.4103/0973-1296.133291

Research Gate: https://www.researchgate.net/publication/263745441_In_Vivo_skin_hydrati…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

7 Fox, L.T., Gerber, M., Du Preez, J.L., Du Plessis, J. and Hamman, J.H. 2015. Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox. Journal of Pharmacy and Pharmacology, 67(1):96-106.

Boloka: http://hdl.handle.net/10394/14751

ORCiD: https://doi.org/10.1111/jphp.12311

Research Gate: https://www.researchgate.net/publication/265388950_Skin_permeation_enha…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

8 Jacobs, G.A., Gerber, M., Malan, M.M., Du Preez, J.L., Fox, L.T. and Du Plessis, J. 2016. Topical delivery of acyclovir and ketoconazole. Drug Delivery, 23(2):631-641.

Boloka: http://hdl.handle.net/10394/14756

ORCiD: https://doi.org/10.3109/10717544.2014.933283

Research Gate: https://www.researchgate.net/publication/263777202_Topical_delivery_of_…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

9 Chinembiri, T.N., Du Plessis, L.H., Gerber, M., Hamman, J.H. and Du Plessis, J. 2014. Review of natural compounds for potential skin cancer treatment. Molecules, 19(8):11679-11721.

Boloka: http://hdl.handle.net/10394/16337

ORCiD: https://doi.org/10.3390/molecules190811679

Research Gate: https://www.researchgate.net/publication/264636991_Review_of_Natural_Co…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

10 Shahzad, Y., Khan, I.U., Hussain, T., Alamgeer, Serra, C.A., Rizvi, S.A.A., Gerber, M. and Du Plessis, J. 2014. Bioactive albumin-based carriers for tumour chemotherapy. Current Cancer Drug Targets, 14(8):752-763.

Boloka: http://hdl.handle.net/10394/15931

ORCiD: http://dx.doi.org/10.2174/1568009614666141028100640

Research Gate: https://www.researchgate.net/publication/267743009_Bioactive_Albumin-Ba…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

11 Shahzad, Y., Louw, R., Gerber, M. and Du Plessis, J. 2015. Breaching the skin barrier through temperature modulations. Journal of Controlled Release, 202:1-13.

Boloka: http://hdl.handle.net/10394/14758

ORCiD: https://doi.org/10.1016/j.jconrel.2015.01.019

Research Gate: https://www.researchgate.net/publication/271196592_Breaching_the_Skin_B…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

12 Chinembiri, T.N., Gerber, M., Du Plessis, L.H., Du Preez, J.L. and Du Plessis, J. 2015. Topical delivery of 5-fluorouracil from Pheroid™ formulations and the in vitro efficacy against human melanoma. AAPS PharmSciTech, 16(6):1390-1399.

Boloka: http://hdl.handle.net/10394/14760

ORCiD: https://doi.org/10.1208/s12249-015-0328-7

Research Gate: https://www.researchgate.net/publication/276066356_Topical_Delivery_of_…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

13 Viljoen, J.M., Cowley, A., Du Preez, J.L., Gerber, M. and Du Plessis, J. 2015. Penetration enhancing effects of selected natural oils utilized in topical dosage forms. Drug Development and Industrial Pharmacy, 41(12):2045-2054.

Boloka: http://hdl.handle.net/10394/14757

ORCiD: https://doi.org/10.3109/03639045.2015.1047847

Research Gate: https://www.researchgate.net/publication/277522269_Penetration_enhancin…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

14 Kilian, D., Shahzad, Y., Fox, L., Gerber, M. and Du Plessis, J. 2015. Vesicular carriers for skin drug delivery: The Pheroid™ technology. Current Pharmaceutical Design, 21(20):2758-2770.

Boloka: http://hdl.handle.net/10394/14762

ORCiD: https://doi.org/10.2174/1381612821666150428125812

Research Gate: https://www.researchgate.net/publication/275545984_Vesicular_Carriers_f…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

15 Gerber, G.S.F.W., Fox, L.T., Gerber, M., Du Preez, J.L., Van Zyl, S., Boneschans, B. and Du Plessis, J. 2015. Stability, clinical efficacy and antioxidant properties of Honeybush extracts in semi-solid formulations. Pharmacognosy Magazine, 11(44):S337-S351.

Boloka: http://hdl.handle.net/10394/14763

ORCiD: http://dx.doi.org/10.4103/0973-1296.166063

Research Gate: https://www.researchgate.net/publication/277528283_Stability_clinical_e…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

16 Burger, C., Gerber, M., Du Preez, J.L. and Du Plessis, J. 2015. Optimised transdermal delivery of pravastatin. International Journal of Pharmaceutics, 496(2):518-525.

Boloka: http://hdl.handle.net/10394/16001

ORCiD: https://doi.org/10.1016/j.ijpharm.2015.10.034

Research Gate: https://www.researchgate.net/publication/283293144_Optimised_transderma…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

17 Aucamp, M.E., Csongradi, C., Gerber, M. and Du Plessis, J. 2016. A novel RP-HPLC method for the detection and quantification of roxithromycin in topical delivery studies. Die Pharmazie, 71(4):175-176.

Boloka: http://hdl.handle.net/10394/16003

ORCiD: https://doi.org/10.1691/ph.2016.5165

Research Gate: https://www.researchgate.net/publication/302886710_A_novel_RP-HPLC_meth…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

18 Van Zyl, L., Du Preez, J., Gerber, M., Du Plessis, J. and Viljoen, J. 2016. Essential fatty acids as transdermal penetration enhancers. Journal of Pharmaceutical Sciences, 105(1):188-193.

Boloka: http://hdl.handle.net/10394/15979

ORCiD: https://doi.org/10.1016/j.xphs.2015.11.032

Research Gate: https://www.researchgate.net/publication/290480850_Essential_Fatty_Acid…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

19 Kilian, D., Lemmer, H.J.R., Gerber, M., Du Preez, J.L. and Du Plessis, J. 2016. Exploratory data analysis of the dependencies between skin permeability, molecular weight and log P. Die Pharmazie, 71(6):311-319.

Boloka: http://hdl.handle.net/10394/16742

ORCiD: https://doi.org/10.1691/ph.2015.5170

Research Gate: https://www.researchgate.net/publication/305004985_Exploratory_data_ana…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

20 Dwivedi, A., Mazumder, A., Fox, L.T., Brümmer, A., Gerber, M., Du Preez, J.L., Haynes, R.K. and Du Plessis, J. 2016. In vitro skin permeation of artemisone and its nano-vesicular formulations. International Journal of Pharmaceutics, 503(1-2):1-7.

Boloka: http://hdl.handle.net/10394/16743

ORCiD: https://doi.org/10.1016/j.ijpharm.2016.02.041

Research Gate: https://www.researchgate.net/publication/296634097_In_vitro_skin_permea…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

21 Venter, T., Fox, L.T., Gerber, M., Du Preez, J.L., Van Zyl, S., Boneschans, B. and Du Plessis, J. 2016. Physical stability and clinical efficacy of Crocodylus niloticus oil lotion. Revista Brasileira de Farmacognosia/Brazilian Journal of Pharmacognosy, 26(4):521-529.

Boloka: http://hdl.handle.net/10394/16741

ORCiD: https://doi.org/10.1016/j.bjp.2016.03.011

Research Gate: https://www.researchgate.net/publication/303501238_Physical_stability_a…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

22 Mazumder, A., Dwivedi, A., Fox, L.T., Brümmer, A., Du Preez, J.L., Gerber, M. and Du Plessis, J. 2016. In vitro skin permeation of sinigrin from its phytosome complex. Journal of Pharmacy and Pharmacology, 68(12):1577-1583.

Boloka: http://hdl.handle.net/10394/17629

ORCiD: https://doi.org/10.1111/jphp.12594

Research Gate: https://www.researchgate.net/publication/308941588_In_vitro_skin_permea…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

23 Fox, L., Csongradi, C., Aucamp, M., Du Plessis, J. and Gerber, M. 2016. Treatment modalities for acne. Molecules, 21(8):1063.

Boloka: http://hdl.handle.net/10394/18747

ORCiD: https://doi.org/10.3390/molecules21081063

Research Gate: https://www.researchgate.net/publication/306132621_Treatment_Modalities…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

24 Burger C, Shahzad Y, Brümmer A, Du Plessis J, Gerber M. 2017. Traversing the skin barrier through nano-emulsions. Current Drug Delivery, 14(4):458-472.

Boloka: http://hdl.handle.net/10394/18748

ORCiD: http://dx.doi.org/10.2174/1567201813666160824125444

Research Gate: https://www.researchgate.net/publication/306946199_Traversing_the_skin_…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

25 Csongradi, C., Du Plessis, J., Aucamp, M.E. and Gerber, M. 2017. Topical delivery of roxithromycin solid-state forms entrapped in vesicles. European Journal of Pharmaceutics and Biopharmaceutics, 114:96-107.

Boloka: http://hdl.handle.net/10394/20668

ORCiD: https://doi.org/10.1016/j.ejpb.2017.01.006

Research Gate: https://www.researchgate.net/publication/312598304_Topical_delivery_of_…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

26 Fox, L.T., Mazumder, A., Dwivedi, A., Gerber, M., Du Plessis, J. and Hamman, J.H. 2017. In vitro wound healing and cytotoxic activity of the gel and whole-leaf materials from selected aloe species. Journal of Ethnopharmacology, 200:1-7.

Boloka: http://hdl.handle.net/10394/20712

ORCiD: https://doi.org/10.1016/j.jep.2017.02.017

Research Gate: https://www.researchgate.net/publication/313733289_In_vitro_wound_heali…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

27 Chinembiri, T.N., Gerber, M., Du Plessis, L.H., Du Preez, J.L., Hamman, J.H. and Du Plessis, J. 2017. Topical delivery of Withania somnifera crude extracts in niosomes and solid lipid nanoparticles. Pharmacognosy Magazine, 13(51):S663-S671.

Boloka: http://hdl.handle.net/10394/25904

ORCiD: https://doi.org/10.4103/pm.pm_489_16

Research Gate: https://www.researchgate.net/publication/320352242_Topical_Delivery_of_…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

28 Du Preez, J.L., Aucamp, M.E., Burger, C., Gerber, M., Viljoen, J.M., Van Zyl, L. and Du Plessis, J. 2018. Development and validation of the simultaneous determination of artemisone, clofazimine and decoquinate with HPLC. Die Pharmazie, 73(3):139-142.

Boloka: http://hdl.handle.net/10394/26679

ORCiD: https://doi.org/10.1691/ph.2018.7127

Research Gate: https://www.researchgate.net/publication/323830632_Development_and_vali…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

29 Burger, C., Aucamp, M., Du Preez, J., Haynes, R.K., Ngwane, A., Du Plessis, J. and Gerber M. 2018. Formulation of natural oil nano-emulsions for the topical delivery of clofazimine, artemisone and decoquinate. Pharmaceutical Research, 35(10):186.

Boloka: http://hdl.handle.net/10394/30744

ORCiD: https://doi.org/10.1007/s11095-018-2471-9

Research Gate: https://www.researchgate.net/publication/326884088_Formulation_of_Natur…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

30 Marais, S., Du Preez, J.L., Du Plessis, L.H., Du Plessis, J. and Gerber, M. 2019. Determination of lovastatin, mevastatin, rosuvastatin and simvastatin with HPLC by means of gradient elution. Die Pharmazie, 74(11):658-660.

Boloka: http://hdl.handle.net/10394/33691

ORCiD: https://doi.org/10.1691/ph.2019.8192

Research Gate: https://www.researchgate.net/publication/337399487_Determination_of_lov…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

31 Maree S, Du Preez JL, Du Plessis LH, Du Plessis J, Gerber M. 2020. A novel HPLC method developed and validated for the detection and quantification of atorvastatin, fluvastatin, pitavastatin and pravastatin during transdermal delivery studies. Die Pharmazie, 75(5):164-166.

Boloka: http://hdl.handle.net/10394/34597

ORCiD: DOI: 10.1691/ph.2020.0007

Research Gate: https://www.researchgate.net/publication/341355349_A_novel_HPLC_method_…

Google Scholar: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=V…

Sithole MN, Marais S, Maree SM, Du Plessis LH, Du Plessis J, Gerber M. 2021. Development and characterization of nanoemulsions and nano-emulgels for transdermal delivery of statins. Expert Opinion on Drug Delivery, 18(6):789-801.